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Research study of the month | December 2019

Participate in research aimed at relieving hot flushes and night sweats experienced by women after breast cancer 

Researchers in the Monash Women’s Health Research Program are conducting a study to evaluate a potential new treatment aimed at relieving hot flushes and night sweats in women diagnosed with breast cancer who are taking hormone blocking therapy (either tamoxifen or an aromatase inhibitor).
 
While clinical trials have found hormone blocking therapy can significantly reduce the risk of breast cancer coming back (recurring), many women experience menopausal-like symptoms when taking hormone-blocking therapy. While these side effects are mild for many women or lessen over time, some women experience significant symptoms which can be difficult to cope with.
 
The study will determine whether QUE 122 (a small molecule which was found to lessen hot flushes and night sweats in an earlier study) is effective in reducing night sweats and hot flushes in women affected by breast cancer being treated with hormone blocking therapy.
 
You may be eligible to participate if you are:

  • Aged 18 to 70 years
  • Are taking tamoxifen or an aromatase inhibitor (i.e. anastrozole (Arimidex), letrozole (Femara) or exemestane (Aromasin).
  • Are experiencing 7 or more hot flushes/night sweats each day/evening.
  • Are able to attend 6 study visits at the research site over approximately 9 weeks.

This study is taking place at sites in Melbourne, Sydney, Adelaide, Brisbane and Perth.
 
If you are interested in participating or would like further information, please contact the study site closest to you.  

Location  Contact detalis
School of Public Health and Preventive Medicine
Monash University
553 St Kilda Road
MELBOURNE, VIC 3004
Michelle Reading: + 61 3 9903 0836
Email: michelle.reading@monash.edu
Email: womens.health@monash.edu
Gynaecology Research Centre
The Royal Women’s Hospital
Research Precinct, Level 7
Corner Grattan St & Flemington Rd
PARKVILLE, VIC 3052
Shona Darby: + 61 3 8345 2217
Email: gynaecology.research@thewomens.org.au
Keogh Institute for Medical
Research
Sir Charles Gairdner Hospital
1st floor, C Block, QE2 Medical Centre
Hospital Ave
NEDLANDS, WA 6009
Smilja Dragovic: + 61 8 6457 2475
Email: smilja@kimr.org
Breast Endocrine Unit
Royal Adelaide Hospital
Level 5, Room 5E343
1 Port Road
ADELAIDE, SA 5000
Jessica Reid: + 61 8 8222 7779
Email: Jessica.Reid2@sa.gov.au
 
Jessie Bennet: + 61 8 8222 6759
Email: jessie.bennett@sa.gov.au
Menopause Clinic / Endocrine Clinic - Royal North Shore Hospital
Reserve Road
ST LEONARDS, NSW 2065
Yue (Yui) Zhao: + 61 2 9463 1463
Email: Yue.Zhao1@health.nsw.gov.au
ICON Cancer Centre
The Wesley Medical Centre, Level 1,
40 Chasely St
AUCHENFLOWER, QLD 4066
Tori Furner: +61 7 3737 4583
Email: tori.furner@icon.team

For information about hormone blocking therapy, including how the drugs work, why they are beneficial and tips / strategies to help manage side effects, download BCNA’s Hormone therapy and breast cancer booklet on bcna.org.au